Pearls

Beware of PHATS in metabolic syndrome

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Making time to monitor all five risk factors for metabolic syndrome can be challenging in a busy psychiatric setting. But with higher prevalence in persons with psychiatric disorders and/or taking psychotropics,1 this precursor for type 2 diabetes and cardiovascular disease demands your attention.2 The mnemonic PHATS can help you monitor metabolic syndrome risk factors thoroughly and quickly (Table).

Based on National Cholesterol Education Program (NCEP) criteria,3 patients with three of five PHATS elements have metabolic syndrome. A recent study of patients taking atypical antipsychotics suggests that abdominal obesity and elevated fasting blood glucose might be the most accurate and cost-effective indicators; combining these two factors correctly identified 100% of patients with metabolic syndrome.4 Until additional studies can confirm this finding, use NCEP guidelines—the basis for PHATS.

You can easily monitor for metabolic syndrome with a blood pressure cuff, a tape measure, and periodic blood glucose and lipid profiles. An extra minute or two can help prevent metabolic complications in at-risk patients.

Table

PHATS: 3 of 5 positive criteria indicate metabolic syndrome

Pressure>130/85 mm Hg
HDL cholesterol
Abdominal obesityWaist circumference
>102 cm in men
>88 cm in women
Triglycerides≥150 mg/dL
SugarFasting blood glucose
≥110 mg/dL

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