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Comments and Controversies

Off-label bupropion

Vol. 9, No. 11 / November 2010

Bupropion: Off-label treatment for cocaine and methamphetamine addiction” (Pearls, Current Psychiatry, July 2010, p. 52) was a well-written, succinct article addressing a pharmacologic treatment in a difficult population. Bupropion has been utilized to target cravings associated with cocaine and methamphetamine addiction with mixed success.1 Hopefully the cocaine vaccine mentioned in the article will be approved, which will provide clinicians with another agent for treating dual diagnosis patients.

Timothy R. Berigan, DDS, MD
Contract Psychiatrist
Behavioral Health Services
Fort Huachuca, AZ


1. Berigan TR. The many uses of bupropion and bupropion sustained release (SR) in adults. Prim Care Companion J Clin Psychiatry. 2002;4(1):30-32.

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